DNA
Part:BBa_K5310025:Design
Designed by: Elias Pilianidis Group: iGEM24_thessaloniki (2024-09-26)
H3 hairpin
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 45
Illegal EcoRI site found at 68 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 45
Illegal EcoRI site found at 68 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 45
Illegal EcoRI site found at 68 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 45
Illegal EcoRI site found at 68 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 45
Illegal EcoRI site found at 68 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
The structure may not be as stable in vivo as it is shown to be in NUPACK and in vitro experiments.
Source
Designed by our team based on complementarity with hairpins H1,H2 and H4 as well as stability standards (thermodynamics, closing base pairs, loop size).